Figure 3: Spearman's rank correlation analysis for disease onset and ΔR3000 (a) Cognitive symptoms (COG) and ΔR1500 (b) and ΔR2000 (c) Neuromuscular symptoms (NM) and Δ R3000 (d) and affective symptoms (AFF) and ΔR2000 (e). All values showed statistically significant negative correlation (see results). In fi gure (f), qEESI total scores by subset were obtained by adding single scores of our cohort