Background: Noise has been related to several cardiovascular diseases (CVDs) such as coronary heart disease and to their risk factors such as hypertension, but associations with stroke remain under-researched, even if CVD likely share similar pathophysiologic mechanisms. Aim: The objective of the study was to examine the association between long-term residential exposure to total environmental noise and stroke incidence in Montreal, Canada. Materials and Methods: We created an open cohort of adults aged ≥45years, free of stroke before entering the cohort for the years 2000 to 2014 with health administrative data. Residential total environmental noise levels were estimated with land use regression (LUR) models. Incident stroke was based on hospital admissions. Cox hazard models with age as the time axis and time-varying exposures were used to estimate associations, which were adjusted for material deprivation, year, nitrogen dioxide, stratified for sex, and indirectly adjusted for smoking. Results: There were 9,072,492 person-years of follow-up with 47% men; 26,741 developed stroke (21,402 ischemic; 4947 hemorrhagic; 392 had both). LUR total noise level acoustic equivalent for 24 hours (LAeq24h) ranged 44 to 79 dBA. The adjusted hazard ratio (HR) for stroke (all types), for a 10-dBA increase in LAeq24h, was 1.06 [95% confidence interval (CI): 1.03–1.09]. The LAeq24h was associated with ischemic (HR per 10 dBA: 1.08; 95% CI: 1.04–1.12) but not hemorrhagic stroke (HR per 10 dBA: 0.97; 95% CI: 0.90–1.04). Conclusion: The results suggest that total environmental noise is associated with incident stroke, which is consistent with studies on transportation noise and other CVD.

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Context: The association between noise sensitivity and misophonia has not been explored in any population, according to the available literature. Aims: To assess the proportion of misophonia symptoms among young healthy adults, to propose the criteria for high perceived misophonia, and to explore the association between misophonia with noise sensitivity with adjustment for sex, age, perceived anxiety, and depression. Settings and Design: A cross-sectional study on 1132 medical students, aged 21.4 ± 2.1 years. Methods and Material: Misophonia symptoms were self-reported using the Amsterdam Misophonia Scale. Nine criteria for high perceived misophonia are proposed. Noise sensitivity was measured with Weinstein scale. Perceived anxiety and depression were measured using the Hamilton Anxiety Rating Scale and the Hamilton Depression Rating Scale, respectively. Statistical Analysis Used: Multiple logistic regression. Results: Almost half of the students reported the feeling of irritation against people making provoking sounds. Only one in 10 claimed the feeling of loss of self-control when exposed to provoking sounds. High noise sensitivity and high depression were associated with higher odds of meeting the criteria for high perceived misophonia. Conclusion: Noise-sensitive students are at higher risk of reporting misophonia symptoms and of being classified with high perceived misophonia. The combination of at least four or more symptoms, which classifies every 10th student with high perceived misophonia, is proposed as a self-assessment tool for epidemiological studies among young healthy adults.

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Context Young people expose themselves to high levels of noise during various leisure activities and might thus be at risk of acquiring hearing-related problems due to leisure noise exposure. Aim The aim of this study was to compare the hearing status, amount of leisure noise exposure, and attitudes and beliefs toward noise, hearing loss, and hearing protection devices (HPDs) in university students at the moment of their enrollment in higher education and after approximately 3 years. Settings and Design Thirty-four female university students were tested at the moment of their enrollment in higher education and after approximately 3 years. Method and Material Hearing was evaluated using pure-tone audiometry and transient evoked and distortion product otoacoustic emissions. A questionnaire was used to evaluate leisure noise exposure and attitudes and beliefs toward noise, hearing loss, and HPDs. Results There were significant differences after the 3-year period: a deterioration in hearing at some tested frequencies, an increase in the occurrence of temporary tinnitus after leisure noise exposure, an increase in noise exposure related to visiting nightclubs and music venues, and differences in attitudes and beliefs toward noise, hearing loss and HPDs. Conclusions More longitudinal studies are needed to evaluate the onset and progression of hearing loss due to leisure noise exposure. In the meantime, hearing conservation programs targeting young people should be optimized.

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Purpose: In this study, the development of a quantitative measurement method to predict long-term auditory adaptation through the stimuli that have been modulated according to different short-term modulation types was aimed to form a psychoacoustic test battery. It might be used in the evaluation process of individuals with hidden hearing loss. Methods: The individuals participating in our study were separated into two groups: high-risk group (n = 39) and low-risk group (n = 30) according to the noise-exposure score. To all participants, auditory brainstem response (ABR), dichotically digit test, Turkish matrix sentence test, otoacoustic emissions test, amplitude modulation detection test, and loudness adaptation test were applied. Stimuli, used in loudness adaptation tests, were provided in three different experiment pairs (experiment 1–2, experiment 3–4, and experiment 5–6). Results: The amplitude of wave I of ABR increased as the intensity level increased in the low-risk group, whereas the amplitude reduced as the intensity level increased in the high-risk group (P < 0.05). When different carrier frequency stimuli were used in amplitude modulation detection test, we found that loudness adaptation was highest at 1 kHz carrier frequency with background noise (P < 0.05). Conclusion: We observed that individuals assumed having hidden hearing loss had high adaptation scores. It was thought that this result might be related to auditory nerve fibers with low spontaneous rate and thus distortion in temporal coding skills might lead to abnormal loudness adaptation, especially with contralateral noise.

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Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is commonly encountered in audiologic and otolaryngologic practice. Constraint-induced music/sound therapy (CIMT) is characterized by the plugging of the normal ear (constraint) and the simultaneous, stimulation of the affected ear with music, which is based on a well-established neurorehabilitation approach. Corticosteroid therapy (CST) is the current mainstay of treatment. The prognosis for hearing recovery depends on many factors including the severity of hearing loss, age, and presence of vertigo. Objective: To analyze the effectiveness of CIMT with CST in ISSNHL. Methods: We performed a systematic search, using specific keywords relevant to our study, in PubMed, Cochrane Central Register of Controlled Trials, and additional sources of published trials till December 2020. We then screened all search results obtained according to our inclusion/exclusion criteria and performed a quality assessment on all studies using the Newcastle–Ottawa scale and using MedCalc, a meta-analysis was performed on suitable studies. Results: The recovery rates of three included nonrandomized studies were assessed at 1 to 3 months. A total of 229 (CST: 131, CST + CIMT: 98) patients were pooled for meta-analysis. The meta-analysis using the random-effect model found the relative risk of recovery rate within 3 months to be 1.213 (95% confidence interval 0.709–2.074), a result that is not statistically significant. Conclusion: Although our analysis results do not demonstrate the noticeable effect of CIMT in ISSNHL, it can support be a gainful adjunct to CST for better hearing results than CST alone. Therefore, it needs further prospective randomized controlled multicenter trials with a large sample.

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Context: There is a need for a clear cutoff to use noise sensitivity (NS) scale as a prediagnostic tool in research and clinical use. Aims: Noise sensitivity questionnaire (NoiSeQ) was adapted into Turkish language (Tr-NoiSeQ); validity and reliability of the Tr-NoiSeQ were assessed. The cutoff for the Tr-NoiSeQ was determined. Settings and design: A descriptive study within subject design. Materials and methods: A group of 402 participants aged between 18 and 52 years filled the Tr-NoiSeQ and the Turkish version of Weinstein noise sensitivity scale (Tr-WNSS) via internet. Statistical analysis used: Cronbach alpha (α) and the Spearman‒Brown coefficient were calculated for the reliability; Pearson correlation coefficient (r) and confirmatory factor analysis (CFA) were used for the validity. The receiver-operating characteristic (ROC) curve was used to calculate cutoff value of the Tr-NoiSeQ. Results: For the Tr-NoiSeQ, Cronbach α was 0.92, Spearman‒Brown coefficient was 0.93 (P < 0.05). A high significant correlation between the Tr-WNSS and the Tr-NoiSeQ was obtained (r = 0.76, P < 0.05). The fit indexes of the model were obtained as (χ² = 1361.06, df = 546, P < 0.001), χ² / df = 2.49, root mean square error of approximation = 0.06, comparative fit index = 0.83, goodness of fit index = 0.82. The ROC curve showed that the cutoff for the Tr-NoiSeQ was 53 with a 0.92 sensitivity and a 0.85 specificity (P ≤ 0.05). Conclusion: The Tr-NoiSeQ is a valid and reliable tool for use in both clinical practice and research. The Tr-NoiSeQ seems to be consistent with the Tr-WNSS and can be used as a screening tool to evaluate NS in audiology.

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Context: With the changing lifestyle in modern society, the youth has become the target of substantial noise exposure. Both environmental noise and the use of personal electronic devices create a risk for youth’s hearing conservation as reported in several studies. Aims: This study aims to adapt and validate the Youth Attitude to Noise Scale (YANS), developed by Widén and Erlandsson for use in the Turkish setting. Settings and Design: The linguistic adaptation of the YANS into Turkish (YANS-Tr) was conducted with three experts in linguistics. A cross-sectional study was designed for high school students to establish the evidence for the reliability and validity of the scale. Methods and Material: 345 high school students participated in the pilot study. The demographic data form developed by the researcher was used to retrieve the information related to participants. Lastly, the 19-item YANS-Tr was delivered to students. Statistical analysis used: Exploratory and confirmatory factor analyses were performed for the construct validity. The Cronbach’s alpha coefficients were calculated for each dimension and the whole scale. Results: Four-dimensional structure was yielded for the YANS-Tr as in the original version of the scale. However, some items (8th, 10th, 18th, and 19th) were loaded under different dimensions. The reliability coefficient of the scale (Cronbach’s α = 0.79) was within the acceptable range. The mean overall YANS-Tr score was 2.68. When the mean scores are compared with other countries, Turkey stands higher than Sweden (2.10), close to Serbia (2.76) and Brazil (2.80), and lower than Belgium (3.10) and China (3.46). Conclusions: The YANS-Tr is shown to be a valid and reliable assessment tool to evaluate the students’ attitude to noise in Turkey.

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